Maxilloethmoidal carcinoma is an uncommon but formidable disease. It is usually discovered only in an advanced stage. The first signs of its presence result from erosive extension beyond the primary area. It is not often possible to designate the precise mucosal area of origin. The contiguous spaces of the maxillary antrum and the ethmoidal labyrinth are usually completely involved. Only occasionally is anterior and inferior disease evidenced through the alveolus or palate before the posterior and superior recesses harbor carcinoma. The assumption of limited disease as an indication for limited treatment more often than not costs the patient his life after a delusional period of "control."
Unfortunately bleeding is not a usual or early first symptom. The relatively functionless area is not subject to symptomatic disturbance. Erosive extension through the maxillary box or polypoid extrusion from the ethmoid labyrinth are the usual and late first symptoms. Early diagnosis by presently
HILGER JA. Maxilloethmoidal Carcinoma. Arch Otolaryngol. 1961;73(2):169–171. doi:10.1001/archotol.1961.00740020175005