Sarcoidosis is a chronic granulomatous disease of unknown etiology. Sarcoidosis of the mucous membranes occurs much less frequently than does involvement of lymph nodes, lungs, liver, spleen, or bones. When it does occur, it is almost always attended by involvement of the other organ systems, particularly the lymphatics. Involvement of the nasal mucosa was present in one of Boeck's original cases. Kistner and Robertson1 reported a case in which this disease affected only the nasal mucous membranes, the nasal bones, and the skin of the nose. Reisner2 studied 35 patients with sarcoidosis, in 4 of whom the mucous membranes were involved.
Rubin and Kling3 reported a case of sarcoidosis of the nasal septum with upward extension and infiltration into the nasal bones and overlying skin. The only other manifestation of the disease was in the terminal phalanx of the patient's right fifth finger. The typical roentgenographic pattern
CRESTON. JE, DIBBLE. PA. Nasal Sarcoidosis. Arch Otolaryngol. 1961;74(2):210–212. doi:10.1001/archotol.1961.00740030215016