A man, aged 60, was seen for the first time at the Chicago-Wesley Memorial Hospital on Sept. 5, 1951, because of a localized swelling at the left side of the nose that had been present for about 5 months. In recent months another more diffuse swelling had extended towards the inner angle and lower lid of the eye, resulting in some epiphora and difficulty in looking downward. There had been no pain at any time, and the skin overlying the lesion was intact. The patient had also noticed a watery discharge and obstruction to breathing in the left nasal passage during all this time. Other than this local pathology, the patient felt quite well and had no complaints.
Examination revealed a firm subcutaneous swelling over the left side of the nose. Nearer to the left eye, the lesion appeared more intimately connected with the overlying skin although this was intact.
HAGENS EW. Corticotropin in Lethal Granuloma of Nose and FaceSupplementary 10-Year Report of a Case So Treated. Arch Otolaryngol. 1962;76(2):183–187. doi:10.1001/archotol.1962.00740050189014