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Comment & Response
March 2014

Obesity and Laryngopharyngeal Reflux as Risk Factors of Lingual Tonsil Hypertrophy in Patients With Sleep-Disordered Breathing: Validity of the Statistical Approach

Author Affiliations
  • 1Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Otolaryngol Head Neck Surg. 2014;140(3):279-280. doi:10.1001/jamaoto.2013.6453

To the Editor I read with interest the study by Sung et al1 for 97 patients with sleep-disordered breathing. They concluded that laryngopharyngeal reflux and body mass index were independent risk factors of lingual tonsil hypertrophy (LTH). I present some statistical concerns about their study.

First, they described that multiple stepwise regression analyses were performed for the risk assessment. But they presented significant and insignificant factors simultaneously in their Table 3. I suppose that they used forced entry method instead of stepwise selection method.

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