KAREN H.CALHOUNMDRONALD B.KUPPERSMITHMD
AS CAN BE seen from Ferguson's review of the literature and treatment options, AFRS remains an enigma to us 17 years after it was described. What we have learned raises many more questions than we have answers.
To address some of the issues raised in her review, we believe that IT may prove to be the next advance in our treatment regimen for AFRS; however, some of the problems with IT include the following: (1) the exact fungus causing the patient's problem must be identified; (2) antigens are not available for all fungi, necessitating the use of similar fungal antigens; (3) IT appears to only control, not eliminate, the disease in some patients; and (4) we do not know whether the disease will recur after IT is finished.
Kuhn FA, Javer AR. Allergic Fungal RhinosinusitisOur Experience. Arch Otolaryngol Head Neck Surg. 1998;124(10):1179-1180. doi:10.1001/archotol.124.10.1179