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Comment & Response
August 25, 2016

Surgical Treatment for T4 Oropharyngeal Cancer

Author Affiliations
  • 1The University of Texas MD Anderson Cancer Center, Houston
JAMA Otolaryngol Head Neck Surg. Published online August 25, 2016. doi:10.1001/jamaoto.2016.2242

To the Editor The article by Zenga et al1 on the role of surgery for T4 oropharyngeal cancer was interesting, but I believe it had several omissions that add to the limitations. The most problematic issue with the analysis was the inherent bias in a comparison between 2 groups, 1 that undergoes the therapy (surgery) and 1 that does not, when the latter group has patients who either medically or technically cannot receive the therapy.

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