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Pathology Forum
May 2000

Quiz Case 2

Arch Otolaryngol Head Neck Surg. 2000;126(5):676-680. doi:

Cat-scratch disease is an infectious disease that occurs when the bacterium Bartonella (formerly Rochalimaea) henselae is transmitted to humans via contact with an infected cat. Any organ system can be involved, although the most common clinical manifestation is benign, self-limited, regional lymphadenopathy. The first case report describing this condition was published in 1950,1 but the cause of CSD eluded detection until 1983, when Wear et al,2 using the Warthin-Starry stain, identified small, pleomorphic, gram-negative, agyrophilic bacilli in lymph nodes of patients with CSD. Compelling evidence that the organism identified by Wear and colleagues is the causative agent of CSD began to accumulate in the early 1990s.3,4

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