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Clinical Problem Solving: Pathology
March 01, 2008

Pathology Quiz Case 1: Diagnosis

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Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2008

Arch Otolaryngol Head Neck Surg. 2008;134(3):335. doi:

Primary mucoepidermoid carcinomas (MECs) of the thyroid gland are extremely rare neoplasms, with fewer than 35 cases reported, to our knowledge.1Mucoepidermoid carcinomas are typically found in salivary tissue, although they have been reported in the larynx, esophagus, breasts, and lungs.2Like MECs of salivary tissue, MECs of the thyroid contain both epidermoid and mucinous elements. In 1991, Chan et al3described a pathologic variant of MEC of the thyroid gland, termed SMECE, as a distinctive low-grade carcinoma of the thyroid gland. There have been even fewer reports of this malignant neoplasm: 23, to date.4

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