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Clinical Note
March 2001

Familial Bilateral Vocal Cord Paralysis and Charcot-Marie-Tooth Disease Type II-C

Author Affiliations

From the Department of Pediatric Otolaryngology, Children's Hospital Medical Center, Cincinnati, Ohio.

Arch Otolaryngol Head Neck Surg. 2001;127(3):322-324. doi:10.1001/archotol.127.3.322

Bilateral abductor vocal cord paralysis (BAbVCP) in children is most frequently caused by congenital abnormalities of the central nervous system, surgery, or birth trauma, although the precise etiology is often unknown. Central nervous system conditions include hydrocephalus, Chiari malformation, and meningomyelocele. Hereditary motor and sensory neuropathy, also called Charcot-Marie-Tooth disease (CMT) or peroneal muscular atrophy, very rarely causes BAbVCP. We describe 3 members of the same family with BAbVCP due to CMT type II-C, all of whom required surgical intervention. Although such an association is rare, CMT should be considered in the differential diagnosis of BAbVCP, and other features of the disease should be sought on history and physical examination. Particular attention to family history and subtle physical signs ensures early diagnosis and appropriate treatment of both patient and affected family members.

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