[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.0.26. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Radiology Forum
June 2001

Diagnosis Quiz Case 1

Author Affiliations
 

R. NICKBRYANMDS. JAMESZINREICHMD

Arch Otolaryngol Head Neck Surg. 2001;127(6):716. doi:

Contrast-enhanced MRI scans of the brain revealed low-signal hemosiderin deposition on the surface of the brain that resembled a thin, black pencil line. The regions involved included the brainstem and the cerebellum.

Superficial siderosis, which was first described by Hamill1 in 1908, is a rare entity characterized by a combination of sensorineural hearing loss, cerebellar ataxia, dementia, and pyramidal signs. It is caused by chronic, sometimes intermittent, subarachnoid hemorrhage, often resulting in progressive mental deterioration.2 Pathologically, there is deposition of hemosiderin in those parts of the central nervous system that are in close proximity to cerebrospinal fluid (CSF), including meninges, subpial tissue, spinal cord, and cranial nerves. This deposition of hemosiderin is associated with gliosis, neuronal loss, and demyelination. It is thought that the cochlear nerve and the cerebellar cortex are particularly vulnerable owing to their accelerated ferritin synthesis.3

First Page Preview View Large
First page PDF preview
First page PDF preview
×