Clinical Note
December 2001

Eagle Syndrome Produced by a Granular Cell Tumor

Author Affiliations

From the University of Mannheim Medical School, Mannheim, Germany (Dr Philipp); and the Departments of Pathology (Dr Barnes) and Otolaryngology (Dr Carrau), University of Pittsburgh Medical Center, Pittsburgh, Pa.


Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

Arch Otolaryngol Head Neck Surg. 2001;127(12):1499-1501. doi:10.1001/archotol.127.12.1499

Eagle syndrome includes elicitation of pain on swallowing, turning the head, or extending the tongue. The syndrome is thought to be caused by irritation of the glossopharyngeal nerve, most commonly caused by its impingement against an elongated styloid process. We present a rare case of a granular cell tumor presenting as Eagle syndrome. Granular cell tumors orignate from Schwann cells and are most common in the subcutaneous tissue of the head, neck, and oral cavity, especially the tongue. A granular cell tumor is typically benign and solitary, rarely malignant. The differential diagnosis, diagnostic algorithm, and treatment are presented.