To test or not to test? In the evaluation of children with SNHL, clinicians have pondered this same question but for different tests through successive eras in medicine. The utility of laboratory testing, electrocardiography, radiologic imaging, nuclear medicine studies, and subspecialty consultation has been and continues to be hotly debated. To this ongoing controversy, we can now add molecular genetic testing and ponder its value. In their review, Greinwald and Hatnick raise important diagnostic, management, and ethical questions about screening patients for mutations in Cx26 while highlighting the benefits of genetic testing. My own practice has been influenced by my experiences in the clinic and the laboratory.
Lalwani AK. Evaluation of Childhood Sensorineural Hearing Loss in the Post-Genome World. Arch Otolaryngol Head Neck Surg. 2002;128(1):88-89. doi:10.1001/archotol.128.1.88