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Clinical Challenges in Otolaryngology
April 2002

Papillary Carcinoma in a Thyroglossal Duct Remnant

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2002;128(4):461-462. doi:10.1001/archotol.128.4.461

For papillary carcinoma in a thyroglossal duct remnant, complete wide excision of the remnant is adequate treatment.

Thyroglossal duct remnants (TGDRs) result from aberrant embryological development of the thyroid gland. During the fourth week of fetal development, the thyroid anlage arises from epithelium located in the floor of the pharyngeal gut and descends as a bilobed diverticulum. During its descent, the thyroid gland remains connected to the base of the tongue by the thyroglossal duct, which involutes as the thyroid reaches its final position in the neck by the eighth week of gestation. Persistence of this embryonic duct results in TGDRs.

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