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Clinical Note
August 2003

Parathyromatosis and Recurrent Hyperparathyroidism

Author Affiliations

From the Division of Otolaryngology, Department of Surgery, University of Louisville School of Medicine, Louisville, Ky. The authors have no relevant financial interest in this article.

Arch Otolaryngol Head Neck Surg. 2003;129(8):894-896. doi:10.1001/archotol.129.8.894

Parathyromatosis is an uncommon cause of hypercalcemia. We describe a case of parathyromatosis and hypercalcemia in a 38-year-old man with a history of end-stage renal disease and subtotal parathyroidectomy in which a previous parathyroid operation was implicated. The results of fine-needle aspiration and histologic examination demonstrated a neck mass consistent with parathyromatosis. We discuss parathyromatosis as a rare cause of recurrent hypercalcemia in patients with end-stage renal disease and in those who have undergone previous parathyroid operations. We also characterize the iatrogenic and the embryologic pathogenetic factors involved.