FREDERIC B.ASKINMDWILLIAM H.WESTRAMD
A 71-YEAR-OLD woman presented with a 3-year history of intractable nasal blockage with fetid purulent discharge, accompanied by intermittent blood-tinged postnasal dripping and low-grade fever. She denied weight loss or cold sweating. Nasal Wegener granulomatosis (WG) was diagnosed at another medical center because the findings of a nasal biopsy were thought to be consistent with that diagnosis, although the results of cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) tests were negative. After receiving steroid therapy, without relief of symptoms, the patient was referred to our center for further evaluation and treatment.
Chen H, Cheng P, Tsai C. Pathology Quiz Case. Arch Otolaryngol Head Neck Surg. 2003;129(10):1135-1136. doi:10.1001/archotol.129.10.1135