Objective: To compare the incidence of residual pathologic disease in the neck between complete and incomplete responders after primary radiation or concurrent chemoradiation for N2 and N3 squamous cell carcinoma of the head and neck.
Design: Retrospective chart review.
Setting: Academic tertiary care medical center.
Patients: A consecutive series of 28 patients with previously untreated squamous cell carcinoma of the oral cavity, oropharynx, nasopharynx, hypopharynx, and larynx with N2 or N3 nodal disease treated with definitive radiation followed by planned neck dissection between January 1998 and January 2006 at the SUNY Upstate Medical University Department of Otolaryngology. Twenty-six of the 28 patients also underwent concurrent chemotherapy. Patients treated with primary surgery were excluded.
Park BJ, Hsu JM. P010 The Correlation of Clinical to Pathologic Neck Response After Radiation or Chemoradiation of N2-N3 Head and Neck Cancer. Arch Otolaryngol Head Neck Surg. 2006;132(8):867. doi:10.1001/archotol.132.8.867-b