[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 184.73.17.193. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Poster Presentations: American Head and Neck Society
August 2006

P060 Significance of Insulinlike Growth Factor Receptor I in the Development of Anaplastic Thyroid Cancer

Arch Otolaryngol Head Neck Surg. 2006;132(8):877. doi:10.1001/archotol.132.8.877-b

Objective: To determine if loss of expression of phospho–insulinlike growth factor (p-IGF) receptor IGF IR in human thyroid cancer specimens correlates with progression to anaplastic disease and responsiveness to anti–IGF-IR therapy.

Design: Retrospective histopathologic study with institutional review board approval

Subjects: Expression levels of IGF-I, pIGF-IR, IGF-IR, Akt, and pAKT were evaluated in 36 thyroid cancer specimens, 6 normal thyroid glands, and thyroid tissue arrays using an immunoperoxidase assay.

First Page Preview View Large
First page PDF preview
First page PDF preview
×