Objective: To assess tumor markers in oropharynx cancer.
Design: Marker expression and clinical outcome.
Patients: Forty-two patients with advanced oropharyngeal cancer treated with chemoradiation therapy.
Intervention: Treatment with chemoradiation therapy.
Main Outcome Measures: Expression of p53 and Bcl-xL in tumor tissues was assessed for correlation with chemotherapy response and survival.
Kumar B, Lee JS, Cordell KG, Prince ME, Wolf GT, Urba SG, Worden FP, Chepeha DB, Eisbruch A, Tsien C, Taylor JMG, Bradford CR, Carey TE. P186 p53 and Bcl-xL Expression Predicts Outcome in Patients With Oropharynx Cancer Treated With Chemoradiation. Arch Otolaryngol Head Neck Surg. 2006;132(8):901. doi:10.1001/archotol.132.8.901-a