Objective: To determine the regional control of locoregional advanced head and neck squamous cell carcinoma (HNSCC) treated with intensity-modulated radiotherapy (IMRT).
Design: Retrospective study.
Setting: Academic center.
Patients: From December 1999 to July 2005, 100 patients with stage N2A or higher HNSCC were treated with definitive IMRT. Five patients who had neck dissection before radiation and 4 with nasopharyngeal cancer were excluded. One patient lost to follow-up 9 months after treatment was also excluded. The remaining 90 patients were analyzed. For IMRT, 3 clinical target volumes (CTVs) were defined and treated with 70 Gy (CTV1), 60 Gy (CTV2), and 54 Gy (CTV3), respectively. Neck dissection was performed for patients who had residual lymphadenopathy after IMRT and who were surgical candidates.
Yao M, Hoffman HT, Smith RB, Funk GF, Chang K, Clamon GH, Dornfeld KJ, Buatti JM. S022 Is Planned Neck Dissection Necessary for Head and Neck Cancer Treated With Intensity-Modulated Radiotherapy?. Arch Otolaryngol Head Neck Surg. 2006;132(8):843. doi:10.1001/archotol.132.8.843-a