Objective: To determine the sensitivity and specificity of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) assay for head and neck squamous cell carcinoma (HNSCC) disease surveillance.
Design: SELDI-TOF-MS serum protein profiles of patients with HNSCC were analyzed to determine the sensitivity and specificity of the SELDI assay for HNSCC detection.
Subjects: Thirty-two patients with previously untreated HNSCC.
Gourin CG, Moretz WH, Weinberger PM, Xia Z, Liu Z, Terris DJ, Adam B. S065 Serum Protein Profile Analysis Following Definitive Treatment in Patients With Head and Neck Squamous Cell Carcinoma. Arch Otolaryngol Head Neck Surg. 2006;132(8):853. doi:10.1001/archotol.132.8.853-a