Objective: Previous publications have reported the predictive utility of apoptotic proteins such as Bcl-2 and survivin in head and neck squamous cell carcinoma (HNSCCA) outcomes. Bcl-2 has been described as a conveyor of altered sensitivity to radiotherapy. This study investigates the association between outcomes of patients with HNSCCA treated nonsurgically and the expression of Bcl-2 and survivin.
Design: Retrospective review.
Otto KJ, Zapato M, Muller S, Chen A, Budnick S. S103 The Association of Bcl-2 and Survivin Expression to Disease Outcome in Head and Neck Cancer. Arch Otolaryngol Head Neck Surg. 2006;132(8):861. doi:10.1001/archotol.132.8.861-b