An 82-year-old man was referred for evaluation of his hypopharynx and larynx after a lesion had been noted on surveillance positron emission tomography for previously treated colorectal carcinoma. The scan had been performed because the patient's level of carcinoembryonic antigen had been increasing. He had a history of recurrent prostate carcinoma, which had been treated twice with surgery and radiation therapy, and recurrent colorectal carcinoma, which had been treated with surgery and chemoradiation therapy initially and at the time of recurrence. At presentation, he reported feeling well and had no particular complaints. Specifically, he denied any throat pain, dysphagia, odynophagia, otalgia, dyspnea, change in voice, or recent episodes of pharyngitis. He drank 1 glass of wine a day and used to smoke a pipe but had quit 40 years ago.
Lewis CM, Resto VA, Wu D, Goguen L. Pathology Quiz Case 2. Arch Otolaryngol Head Neck Surg. 2006;132(10):1157. doi:10.1001/archotol.132.10.1157