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Clinical Problem Solving: Pathology
April 2007

Pathology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2007;133(4):414. doi:10.1001/archotol.133.4.414

Actinomycosis is rare nowadays because of its high sensitivity to most antibiotics and because of a general improvement in oral hygiene. Actinomycosis of the lip is very uncommon. A review of the English-language medical literature revealed only 1 reported case of lip involvement over the last 30 years.1 We describe a smooth, nonulcerative, firm submucosal lesion of the lip that had the clinical appearance of a minor salivary gland tumor. Diagnosis of actinomycosis was confirmed only after histologic examination revealed the characteristic picture of sulfur granules.

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