Silicone prosthesis for either joints or plastic surgical procedures, specifically breast augmentation, has been documented to cause enlargement in local lymph node groups.1,2 Inflammatory reactions in foreign bodies containing silicone have been noted within fine-needle aspiration (FNA) and/or histopathologic specimens of enlarged lymph nodes in the setting of silicone breast implants. As the population of women who have received silicone breast implants becomes older, greater incidence of implant leakage is expected.3 As a result, more women may present with local lymphadenopathy caused by silicone foreign body reaction.
Shipchandler TZ, Lorenz RR, McMahon J, Tubbs R. Supraclavicular Lymphadenopathy Due to Silicone Breast Implants. Arch Otolaryngol Head Neck Surg. 2007;133(8):830-832. doi:10.1001/archotol.133.8.830