Clinical Note
August 2007

Supraclavicular Lymphadenopathy Due to Silicone Breast Implants

Author Affiliations

Author Affiliations: Head and Neck Institute (Drs Shipchandler and Lorenz) and Department of Pathology (Drs McMahon and Tubbs), Cleveland Clinic, Cleveland, Ohio.


Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007

Arch Otolaryngol Head Neck Surg. 2007;133(8):830-832. doi:10.1001/archotol.133.8.830

Silicone prosthesis for either joints or plastic surgical procedures, specifically breast augmentation, has been documented to cause enlargement in local lymph node groups.1,2 Inflammatory reactions in foreign bodies containing silicone have been noted within fine-needle aspiration (FNA) and/or histopathologic specimens of enlarged lymph nodes in the setting of silicone breast implants. As the population of women who have received silicone breast implants becomes older, greater incidence of implant leakage is expected.3 As a result, more women may present with local lymphadenopathy caused by silicone foreign body reaction.

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