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Clinical Note
May 17, 2010

Adult Xanthogranuloma Causing Nasal Obstruction

Author Affiliations

Author Affiliations: Department of Otolaryngology–Head and Neck Surgery, Stanford University Hospitals and Clinics, Stanford, California.

Arch Otolaryngol Head Neck Surg. 2010;136(5):509-512. doi:10.1001/archoto.2010.44

Adult xanthogranuloma (AXG) is a rare histiocytic disease that produces predominantly cutaneous lesions. We describe a female patient with AXG who developed xanthogranulomatous lesions within the nasal vestibule, bilaterally producing progressive nasal obstruction. A septorhinoplasty with excision of the nasal xanthogranuloma was initially successful at improving her nasal obstruction. However, within weeks, regrowth of the lesion again began producing progressive narrowing of the nasal vestibules. A comprehensive review of the English-language literature revealed only 1 other case with this presentation in an adult.1 We discuss this interesting case and present a brief review of the disease process.

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