The parapharyngeal space (PPS) is a rare site for neoplasms in the head and neck, representing only 0.5% of head and neck tumors. Most commonly of parotid and neurogenic origin, tumors of the PPS are histologically diverse. Lipomas of the PPS are rare and liposarcomas rarer still. Only 5 liposarcomas of the PPS have been previously reported (Table). We describe our experience at the University of South Florida (USF), Tampa, with this unusual entity in this review of 2 lipomas, 1 pleomorphic liposarcoma, and 1 dedifferentiated liposarcoma of the PPS. To our knowledge, dedifferentiated liposarcoma has not previously been described in the PPS.
Rogers J, Patil Y, Strickland-Marmol L, Padhya T. Lipomatous Tumors of the Parapharyngeal SpaceCase Series and Literature Review. Arch Otolaryngol Head Neck Surg. 2010;136(6):621-624. doi:10.1001/archoto.2010.93