Clinical Challenges in Otolaryngology
January 1999

Value of Neck Dissection in the Treatment of Patients With Intermediate-Thickness Cutaneous Malignant Melanoma of the Head and Neck

Author Affiliations

From the Department of Surgery, University of Texas M. D. Anderson Cancer Center, Houston.




Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999

Arch Otolaryngol Head Neck Surg. 1999;125(1):110-115. doi:10.1001/archotol.125.1.110

Hypothesis: An elective neck dissection is required in the treatment of intermediate-thickness (1-4 mm) cutaneous malignant melanoma of the head and neck (CMMHN).

The role of cervical lymphadenectomy in the treatment of patients with intermediate-thickness CMMHN and with no other clinical evidence of disease has been an area of controversy among surgical oncologists specializing in the head and neck for several decades. A recent increase in the incidence of melanoma and new advances in the evaluation and treatment of this disease mandate a critical reappraisal of the role of neck dissection in managing melanomas that arise from the skin of the head and neck. I review prevailing epidemiological trends in melanoma and developments in surgery, biologic therapy, and radiation therapy for CMMHN and place the arguments for and against elective lymph node dissection (ELND) in the context of these technological advances.

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