R. NICKBRYANMDS. JAMESZINREICHMD
Plasma cell neoplasms usually form multiple tumors in bone, resulting in generalized bone marrow plasmacytosis, such as multiple myeloma. Rarely, they may also present as localized plasma cell malignancies and may be classified as solitary plasmacytoma of bone (SPB) or extramedullary plasmacytoma (EMP), according to site. The incidence of multiple myeloma in the United States is approximately 2.8 cases per 100,000 males and 2.1 cases per 100,000 females. Together, SPB and EMP account for fewer than 10% of all plasma cell tumors. Although the relationship between multiple myeloma, SPB, and EMP is not entirely understood, all 3 are considered to be part of the same disease process.
Imaging Quiz Case 1. Arch Otolaryngol Head Neck Surg. 1999;125(3):348-352. doi: