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July 1928

IRRIGATIONS WITH AQUEOUS SOLUTIONTHEIR EFFECT ON THE MEMBRANES OF THE UPPER RESPIRATORY TRACT OF THE RABBIT

Author Affiliations

ROCHESTER, MINN.
From the Section on Otolaryngology and Rhinology, Mayo Clinic.

Arch Otolaryngol. 1928;8(1):47-55. doi:10.1001/archotol.1928.00620020055007
Abstract

Irrigation of the nasal fossae with aqueous solution has been advocated for many years in the treatment of various lesions of the nose. Although a great deal has been said concerning the advantages and the technic of intranasal douching, little has been said concerning the histologic changes which take place following repetition of the procedure. Lillie1 has directed attention to cases in which the nasal mucosa appeared pale, shiny and waterlogged after long-continued irrigation following operation and in which symptoms were relieved and the nasal mucous membranes became more nearly normal when irrigation was discontinued. This occurred frequently enough to indicate that the intranasal douching was responsible for the altered appearance of the nasal mucous membranes. In cases in which operation has not been performed and intranasal irrigations have been used, similar changes in the mucous membrane have been noted. In either case, the picture seen

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