While the incidence of pneumococcus and streptococcus meningitis is fortunately low, present methods of treatment are so unsatisfactory and the mortality so near 100 per cent, despite newer methods of treatment,1 that it would appear worth while to inquire into the possibility of developing methods for the specific prophylaxis for these infections.
Unquestionably, adequate surgical drainage of suppurative foci in the middle ear, the mastoid and the nasal accessory sinuses is of importance in this respect, although in a large percentage of cases, meningitis develops after operations on infected sinuses and other foci because of a breaking down of chronic inflammatory barriers and a stimulation of infection.
Since it is usually possible to determine promptly and before operation the bacteria producing infections of the sinuses and the middle ear and to include bacteriologic examination at the time of operation on the mastoid cells, the question arises whether
KOLMER JA, AMANO KW. THE SPECIFIC PROPHYLAXIS OF PNEUMOCOCCUS AND STREPTOCOCCUS MENINGITISI. SERUM PROPHYLAXIS. Arch Otolaryngol. 1931;14(2):125–138. doi:10.1001/archotol.1931.00630020149001