These tumors, which were studied microscopically, were selected from the group of malignant tumors of the throat seen at the Mayo Clinic in a period of fourteen years, from 1917 to 1930, inclusive. Eighty-eight of them (40 per cent) were seen in the first seven year period, from 1917 to 1923, and 132 (60 per cent) in the second seven year period. Tumors of the nasopharynx are not included in this group. Carcinoma of the mixed tumor type, which is potentially malignant, was considered in study II of this series.
Squamous cell epithelioma in this situation is almost five times more common than all the other malignant tumors. There were 174 of these cases (79.2 per cent). Most of them were of an active type of growth. High grade squamous cell epithelioma, formerly often called endothelioma, or branchiogenic carcinoma, is today described by Europeans, particularly, as lympho-epithelioma and by others
NEW GB, CHILDREY JH. III. MALIGNANT TUMORS EXCLUSIVE OF ADENOCARCINOMA OF THE MIXED TUMOR TYPE (TWO HUNDRED AND TWENTY CASES). Arch Otolaryngol. 1931;14(6):713–730. doi:10.1001/archotol.1931.03580020804002