Otologists have long recognized the necessity and desirability of treating the eustachian tube in varied conditions. The majority of such treatments have been mechanical, although numerous medicaments have been applied locally. This has been accomplished directly by means of applicators or by blowing liquids into the tube through a eustachian catheter.
Solutions, owing to many obvious disadvantages, have not continued in wide use and have been abandoned in favor of vapors which are blown into the eustachian tube to inflate both it and the middle ear. Vapors of iodine, ether, chloroform, menthol, camphor, etc., have been used sometimes in heated air. The action of these vapors on the living mucosa has been, for the most part, to increase the vascularity of the part treated.
Until recently no vapor was available which was capable of decreasing the congestion of the lining of the eustachian tube and the middle ear. The vapor
WOOD EL. A NEW DRUG FOR TREATMENT OF THE EUSTACHIAN TUBE AND MIDDLE EAR, WITH AN APPARATUS FOR ITS USE. Arch Otolaryngol. 1935;21(5):588–590. doi:10.1001/archotol.1935.00640020602010