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Article
December 1937

INTRADURAL CONDITIONS IN RELATION TO RHINOLOGY AND OTOLOGYA CRITICAL SURVEY OF RECENT LITERATURE

Author Affiliations

NEWARK, N. J.

Arch Otolaryngol. 1937;26(6):690-735. doi:10.1001/archotol.1937.00650020762005
Abstract

ABSCESS OF THE BRAIN 

GENERAL CONSIDERATIONS  Experimental Production of Abscess of Brain.—Groff149 implanted bacteria directly into the brain substance of a cat. The extreme resistance of the brain to experimental infection suggested that some culture medium on which bacteria are grown must be used. Pneumococcus or Diplococcus pneumoniae, type III, was employed. The pneumococcus loses its toxicity rapidly when subcultured. It was necessary to pass the bacteria through a mouse in order to increase the virulence. The five lesions produced conformed in the gross to pathologic abscesses of the brain. The longest duration of a lesion was eight days following the infection and the shortest three days.Encapsulation of Abscess of Brain.—The brain attempts to wall off any abscess to protect itself against bacteria and their toxins. The capsule consists of younger or older connective tissue, depending on the age of the lesion. Three zones are identified in the connective

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