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Article
September 1945

CARCINOMA OF THE LARYNXSIGNIFICANCE OF HISTOPATHOLOGIC STUDY OF SERIAL SECTIONS; PRELIMINARY REPORT

Author Affiliations

CHICAGO
From the Department of Laryngology, Rhinology and Otology, and the Tumor Clinic, University of Illinois College of Medicine.

Arch Otolaryngol. 1945;42(3):178-185. doi:10.1001/archotol.1945.00680040238005
Abstract

Since the performance of the first total laryngectomy by Billroth and Czerny in 1873, voluminous reports or various aspects of cancer of the larynx have appeared in the literature. Generally, they were concerned with problems of early diagnosis, modes of therapy, surgical technics, histopathologic observations and the radiosensitivity of the growths. As the attention to cancer of the larynx increased, the rate of cures seemed to become larger. This improvement was predicated mainly on earlier recognition of true cordal lesions clinically considered intrinsic and amenable to local removal by laryngofissure. With this method, recent statistical analyses of large series of cases show that on an average cures are obtained in 80 per cent. With laryngectomy, analyses of similar series indicate that on an average cures are possible in approximately 50 per cent. A study of the failures following both types of procedures reveals that local recurrence following laryngofissure is the

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