IT IS now universally accepted that in the body the primary site of multiplication of the meningococcus is the nasopharynx. From this site the organisms may or may not find their way into the blood stream and produce the symptoms of septicemia. When septicemia occurs, the likelihood that there will be a secondary localization in the meninges is great, though many cases of meningococcemia without meningitis have been reported. There may be localizations in many other tissues, such as the joints,1 the structures of the eye,2 the sex organs3 or, more rarely, in the heart or the lungs,4 sometimes without meningitis. All of these localizations are regarded as being secondary to the invasion of the blood stream.
Recently a number of cases of meningococcic conjunctivitis have been reported in which there was no preceding septicemia.5 In these cases, therefore, the infection was either primary in the eye or secondary to
VEAZIE L, SEARS HJ. SEVERE PURULENT INFLAMMATION OF THE UPPER RESPIRATORY TRACT CAUSED BY NEISSERIA INTRACELLULARIS. Arch Otolaryngol. 1947;45(6):632–636. doi:10.1001/archotol.1947.00690010647003