WHEN a clinical entity like cavernous sinus thrombosis, which once had a mortality of almost 100 per cent, has had its devastating picture transformed by the advent of sulfonamides, antibiotics and anticoagulants, it is time to assemble the facts and to reevaluate the subject.
Since 1818, when Abercrombie first described cavernous sinus thrombosis from autopsy observations, surgeons and, particularly otolaryngologists have wrestled with this dreaded complication. For over a hundred years, physicians, knowing the pathologic changes behind this complication, despaired of the patient's life as soon as the diagnosis was made. The extent of their hopes was to get an autopsy to confirm the diagnosis. Overnight the tide has turned. Some of the fear is being banished. While physicians should not be too hopeful of recovery, they at least know that there is the possibility of an outcome more favorable than death.
Thrombosis of the cavernous sinus may strike at
ELFMAN LK. THROMBOSIS OF THE CAVERNOUS SINUSA New Evaluation and Report of a Case with Recovery. Arch Otolaryngol. 1950;51(2):188–195. doi:10.1001/archotol.1950.00700020209004