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December 1965

Juvenile Nasopharyngeal Angiofibroma in a FemaleReport of a Case

Author Affiliations

From the Department of Pathology and the Professional Unit of the Institute of Laryngology and Otology, University of London.

Arch Otolaryngol. 1965;82(6):629-632. doi:10.1001/archotol.1965.00760010631014

THIS UNCOMMON lesion of the upper air passages has been a well-established entity for at least 100 years but its precise nature and origin are still subject to debate. Its tumor-like behavior causing obstruction of the airway and its fibrovascular structure giving rise to severe hemorrhage have long been associated with a predilection for pubescent males. The sex incidence is underlined by the fact that many of the larger published series such as the 29 cases of Martin and associates,1 the 26 cases of Hubbard,2 the 52 cases of Harma,3 and the 9 cases of Patterson4 are exclusively male.

On the other hand, a number of authors have reported the condition as occurring occasionally in females. The earliest record was that of Pluyette5 who reported 12 alleged cases in females but, since many were outside the usually accepted age incidence, it is doubtful whether they

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