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Article
October 1966

Chordoma Arising From Chordoma Notochord Cells

Author Affiliations

PETAH TIKVA, ISRAEL
From the ENT Department, Beilinson Hospital, Petah Tikva, Israel.

Arch Otolaryngol. 1966;84(4):441-443. doi:10.1001/archotol.1966.00760030443015
Abstract

HISTOLOGICALLY the chordoma is a benign tumor, but clinically it is destructive. It develops in the residual notochord along the spine and the base of the skull. The majority of cases of chordoma described up to now occurred at the ends of the notochord, ie, in the spheno-occipital region (35%-40%) and in the sacrococcygeal region (45%-50%) of the spine. The remaining 10%-20% of the cases were distributed over other regions of the spine.1

As is known, the nuclei pulposi of the intervertebral discs consist of notochord tissue. The fact that the chordoma develops more frequently in places in which there is no nucleus pulposus suggests that it originates not in organized notochord tissue but in ectopic tissue. Utne and Pugh2 collected 505 cases of chordoma and found that 39% were in the spheno-occipital region, 45% in the sacrococcygeal region, and 16% along the spine. The average age of

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