In 86 cases of isolated supraclavicular masses, most were metastases from pulmonary primaries. Ten cases were very unusual tumors and eight others were caused by head and neck tumors which had clinically bypassed higher cervical nodes and appeared in the supraclavicular area. Because of the complex anatomy of the area, the presence of the thoracic duct, draining virtually the entire body, and the fact that isolated supraclavicular masses are not common to begin with, it Is suggested that they be approached with all possibilities in mind.
Lundmark GJ, Acquarelli MJ. Unusual Supraclavicular Masses. Arch Otolaryngol. 1970;91(6):529–533. doi:10.1001/archotol.1970.00770040759008