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July 1977

Neonatal Sound Deprivation Affects Brain Stem Auditory Nuclei

Author Affiliations

Molly Webster
From the Kresge Hearing Research Laboratory of the South, Louisiana State University Medical Center, Department of Otorhinolaryngology, New Orleans.

Arch Otolaryngol. 1977;103(7):392-396. doi:10.1001/archotol.1977.00780240050006

• CBA/J mice deprived of airborne sound stimulation during postnatal development have smaller globular cells in the ventral cochlear nucleus and smaller neurons in the medial nucleus of the trapezoid body than do normal control mice. The sound deprivation in these mice is similar to that experienced by persons with pure congenital conductive hearing losses. Even more profound central neural changes were found in auditory nuclei in the brain stem of a congenitally sensorineural deaf human.

(Arch Otolaryngol 103:392-396, 1977)