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August 1981

Hypercalcemia Secondary to a Pseudoparathormone-Secreting Ameloblastoma

Author Affiliations

From the Section on Otolaryngology, Department of Surgery, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC.

Arch Otolaryngol. 1981;107(8):487-490. doi:10.1001/archotol.1981.00790440027007

• An unusual case of hypercalcemia associated with an ameloblastoma occurred. The sequence of recurring ameloblastoma, increased serum calcium levels and urinary cyclic adenosine monophosphate (cAMP) levels, removal of the tumor, and decrease of those levels to normal suggests that the ameloblastoma was secreting a parathormone-like substance that, in turn, was stimulating the production of nephrogenous cAMP and elevating the serum calcium level.

(Arch Otolaryngol 1981;107:487-490)