• One hundred four patients had verrucous carcinomas of the oral cavity. Our study documents, for the first time, the coexistence of foci of less-differentiated squamous carcinoma within verrucous lesions of the oral cavity (20%). We confirm previous observations that verrucous lesions tend to recur in the form of less-differentiated carcinomas. Finally, we demonstrate that surgery is indeed the treatment of choice for verrucous carcinomas of the oral cavity, although irradiation can be used to treat selected patients.
(Arch Otolaryngol 1984;110:437-440)
Medina JE, Dichtel W, Luna MA. Verrucous-Squamous Carcinomas of the Oral CavityA Clinicopathologic Study of 104 Cases. Arch Otolaryngol. 1984;110(7):437–440. doi:10.1001/archotol.1984.00800330019003