• Effects of defibrinogenation therapy and steroid therapy for sudden deafness were compared by paired double-blind testing. The average hearing recovery for five frequencies (250 to 4000 Hz) was more than 30 dB; overall improvement rate was 57.3% (47/82) for the patients assigned to defibrinogenation therapy and 38.7% (31/80) for the patients assigned to steroid therapy. Thus, the former treatment resulted in significantly better hearing recovery.
(Arch Otolaryngol Head Neck Surg 1988;114:649-652)
Kubo T, Matsunaga T, Asai H, Kawamoto K, Kusakari J, Nomura Y, Oda M, Yanagita N, Niwa H, Uemura T, Komune S. Efficacy of Defibrinogenation and Steroid Therapies on Sudden Deafness. Arch Otolaryngol Head Neck Surg. 1988;114(6):649-652. doi:10.1001/archotol.1988.01860180063031