• Sixty-six whole-organ sectioned, nonirradiated, laryngopharyngectomy specimens that were removed because of cancer during a 7-year period were uniformly examined to determine the accuracy of pericperative T staging by high-resolution computed tomography (CT) and clinical evaluation (indirect-direct laryngoscopy) by comparing this preoperative staging with the postsurgical pathologic staging. The accuracy of the clinical vs CT staging for laryngeal carcinomas was 58.8% vs 70.6%, whereas the accuracy of the staging by combination of the two modalities was 88.2%. Combined staging modalities showed the same accuracy for laryngeal and hypopharyngeal carcinomas (88.2%), whereas clinical staging accuracy for hypopharyngeal carcinomas was lower (52.9%) and CT accuracy was higher (82.4%) than that observed for laryngeal carcinomas. In the majority of the cases that were staged inaccurately, the error was one of underestimation: in particular, tumors confined to the mucosa and early infiltration of laryngeal fat spaces were not detected by CT.
(Arch Otolaryngol Head Neck Surg. 1989;115:613-620)
Sulfaro S, Barzan L, Querin F, Lutman M, Caruso G, Comoretto R, Volpe R, Carbone A. T Staging of the Laryngohypopharyngeal CarcinomaA 7-Year Multidisciplinary Experience. Arch Otolaryngol Head Neck Surg. 1989;115(5):613-620. doi:10.1001/archotol.1989.01860290071017