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July 1990

Extramedullary Plasmacytoma of the Thyroid Associated With a Serum Monoclonal Gammopathy

Author Affiliations

From the Department of Otolaryngology (Drs Rubin and Johnson) and Pathology (Drs Killeen and Barnes), University of Pittsburgh School of Medicine and the Eye and Ear Hospital of Pittsburgh (Pa).

Arch Otolaryngol Head Neck Surg. 1990;116(7):855-859. doi:10.1001/archotol.1990.01870070103020

• Extramedullary plasmacytoma is a malignant plasma cell dyscrasia that is most commonly found in the head and neck. Progression to disseminated disease in the form of multiple myeloma occurs in 17% to 32% of cases. Herein, we describe a patient with extramedullary plasmacytoma of the thyroid gland in whom a serum monoclonal gammopathy resolved with surgery and irradiation of the primary. Although rare, this diagnosis should be considered in patients presenting with obstructive thyromegaly and autoimmune thyroiditis.

(Arch Otolaryngol Head Neck Surg. 1990;116:855-859)