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July 1992

Undifferentiated Small-Cell Neoplasm of the Petrous ApexA Case Report

Author Affiliations

From the University of Iowa College of Medicine (Mr Henrich), Departments of Otolaryngology (Drs Gantz and Schubkegel), and Pathology (Dr Moore), University of Iowa Hospitals and Clinics, Iowa City.

Arch Otolaryngol Head Neck Surg. 1992;118(7):767-770. doi:10.1001/archotol.1992.01880070097019

• We present a rare case of undifferentiated small-cell neoplasm involving the temporal bone petrous apex. The symptoms, physical examination, importance of roentgenographic findings, and pathologic findings are reviewed. While not absolutely conclusive, the collective evidence in this case supports a diagnosis of small-cell carcinoma of the lung with metastasis to the petrous apex. A discussion of temporal bone malignancies, their frequencies, and characteristics is included. To our knowledge, a review of the literature over the past 25 years reveals no other published cases of an undifferentiated small-cell carcinoma in the temporal bone.

(Arch Otolaryngol Head Neck Surg. 1992;118:767-770)