The report by Wei and his associates,1 Queen Mary Hospital, The University of Hong Kong, is based on sedulous examination of the contents in classic radical neck specimens. The authors offer a pathological assessment of surgery in the management of postradiotherapy cervical metastases in nasopharyngeal carcinoma.
Salient points in the study are the following: (1) 43 patients of an unknown cohort of treated patients were the test population, (2) the primary in the nasopharynx was "controlled in all 43 patients," (3) the persistent or recurrent cervical lymphadenopathy was always unilateral, (4) only three of 43 neck dissection specimens did not contain metastatic carcinoma, (5) two patients had well-differentiated squamous cell carcinoma (World Health Organization [WHO] I) and 38 had poorly differentiated carcinoma (WHO II, III), (6) of 2137 lymph nodes removed and examined from the 43 patients, 294 (13%) contained metastatic carcinoma, (7) only in seven patients were metastases
BATSAKIS JG. Surgery in the Management of Postradiotherapy Cervical Metastasis. Arch Otolaryngol Head Neck Surg. 1992;118(9):930. doi:10.1001/archotol.1992.01880090046013