In this report, we describe the findings of a noninvasive assessment of the intralabyrinthine pressure in two patients from a family with X-linked progressive, mixed deafness syndrome in whom a perilymphatic gusher occurs during stapes surgery. The so-called tympanic membrane displacement measurement technique could be successfully applied in these two patients (from a total of five patients who were studied) because they still showed a stapedial reflex at 1 kHz, which is mandatory for application of the tympanic membrane displacement measurement technique. The findings were compared with those of age-related control subjects and indicated a significantly elevated intralabyrinthine pressure in the two patients who were observed. The results suggest that the tympanic membrane displacement measurement technique may serve as a screening test in audiological diagnostic studies of perilymphatic hypertension.
(Arch Otolaryngol Head Neck Surg. 1995;121:926-929)
Ernst A, Snik AFM, Mylanus IAM, Cremers CWRJ. Noninvasive Assessment of the Intralabyrinthine PressureA New Technique Applied to Patients With X-linked Progressive Mixed Deafness Syndrome With Perilymphatic Gusher During Stapes Surgery. Arch Otolaryngol Head Neck Surg. 1995;121(8):926-929. doi:10.1001/archotol.1995.01890080092018