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September 1995

Metastatic Melanoma to the Cerebellopontine AngleClinical and Imaging Characteristics

Author Affiliations

From the Department of Otolaryngology, Wilford Hall Air Force Medical Center, Lackland Air Force Base, Tex (Dr Arriaga); the Department of Radiology, St Vincent Medical Center, Los Angeles, Calif (Dr Lo); and the House Ear Clinic, University of Southern California, Los Angeles (Dr Brackmann).

Arch Otolaryngol Head Neck Surg. 1995;121(9):1052-1056. doi:10.1001/archotol.1995.01890090086017

Objective:  To describe the clinical and imaging features of metastatic melanoma to the cerebellopontine angle (CPA).

Design:  A case series study with world literature review.

Setting:  House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif.

Patients:  Three cases of metastatic CPA tumors operated on at the House Ear Clinic.

Interventions:  All patients underwent surgical removal of CPA metastatic melanoma.

Main Outcome Measure:  Survival and duration of disease-free interval are reported.

Results:  Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform.

Conclusions:  Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the longterm prognosis for patients with CPA melanoma is grim.(Arch Otolaryngol Head Neck Surg. 1995;121:1052-1056)