The major risk factors for developing oral cavity squamous cell carcinoma in the United States include smoking, alcohol, syphilis, and herpes simplex virus type 1. It is difficult to locate a report of squamous cell carcinoma arising in association with osseointegrated dental implants, despite their frequent use. We report an unusual series of 3 cases of squamous cell carcinoma arising around an implant.
Arch Otolaryngol Head Neck Surg. 1996;122:1402-1403
Clapp C, Wheeler JC, Martof AB, Levine PA. Oral Squamous Cell Carcinoma in Association With Dental Osseointegrated ImplantsAn Unusual Occurrence. Arch Otolaryngol Head Neck Surg. 1996;122(12):1402-1403. doi:10.1001/archotol.1996.01890240108024